Heathrow rules out compensation for delayed disabled passengers

Disabled passengers who are stranded on planes at Heathrow airport will not be compensated, its chief executive says.

The BBC’s Frank Gardner criticised the airport after he was left waiting for 100 minutes because his wheelchair had been misplaced by ground staff.

CEO John Holland-Kaye said: “I don’t think it’s reasonable that we should take financial responsibility.”

He said Heathrow would aim to help disabled passengers off the plane within 20 minutes of landing.

On Saturday, the BBC’s security correspondent said that airports would only listen to disabled passengers if there was a financial penalty.

MS drug hope for secondary-progressive stage

A study of a new drug to treat advanced cases of multiple sclerosis suggests it may be possible to delay progression of the disease in the short term, although the effects were small.

In a trial of 1,327 people, in The Lancet, 26% saw their disability worsen after three months taking siponimod compared with 32% taking a dummy drug.

No drugs currently exist for secondary-progressive multiple sclerosis.

An MS expert expressed caution, saying other new treatments were still needed.

About 100,000 people in the UK have MS – a lifelong, progressive condition. Most are diagnosed between the ages of 20 and 70.

MS affects the central nervous system and can cause problems with:

  • vision
  • balance
  • fatigue
  • stiffness
  • memory

    Most cases start as relapsing-remitting MS and most of these develop into secondary-progressive MS within 15-20 years.

    ‘Modest effect’

    Patients in this trial, which was funded by drug company Novartis, had had MS for an average of 17 years – four years with secondary MS, the advanced stage.

    Most needed assistance with walking before the trial began.

    When standard measures of disability were used to track their progress, there was a 21% lower risk of walking or arm movements getting worse for those given the drug, compared with those taking the placebo.

    But the international research team found the drug had no effect on maintaining patients’ walking speed and it had some side-effects, although it was still thought to be safe.

    • How I’m feeling after my MS ‘body reboot’ – BBC News
      • Transplant trial gives us our future back

        Lead author Prof Ludwig Kappos, from the University of Basel, said: “Although the results are not as good as we wanted to see, it is a very large study, which is robust.

        “It means siponimod is one option to delay the disease in the advanced stage.”

        Dr Susan Kohlhaas, director of research at the MS Society, said: “These results bring us closer to the first ever treatment for people with secondary-progressive MS – so it’s big news.

        “This trial showed that siponimod had a modest but significant effect in slowing disability progression, which is incredibly encouraging.”

        ‘Disappointing’

        But Dr Luanne Metz, from the University of Calgary, in Canada, said a second trial was needed to confirm the benefits of the drug and its impact beyond three to six months.

        She said: “Although siponimod seems to reduce the time to confirmed disability in secondary-progressive MS, the treatment effect was small.

        “In our opinion… the absence of a significant difference for the key secondary clinical outcome are disappointing results and do not suggest that siponimod is an effective treatment for secondary-progressive MS.”

        She added: “Trials of other novel treatments that target non-inflammatory mechanisms are still needed.”

        Before the drug becomes available on the NHS, it would need to be approved by the European Medicines Agency and then recommended as cost-effective by bodies in the UK.

MS drug hope for secondary-progressive stage

A study of a new drug to treat advanced cases of multiple sclerosis suggests it may be possible to delay progression of the disease in the short term, although the effects were small.

In a trial of 1,327 people, in The Lancet, 26% saw their disability worsen after three months taking siponimod compared with 32% taking a dummy drug.

No drugs currently exist for secondary-progressive multiple sclerosis.

An MS expert expressed caution, saying other new treatments were still needed.

About 100,000 people in the UK have MS – a lifelong, progressive condition. Most are diagnosed between the ages of 20 and 70.

MS affects the central nervous system and can cause problems with:

  • vision
  • balance
  • fatigue
  • stiffness
  • memory

    Most cases start as relapsing-remitting MS and most of these develop into secondary-progressive MS within 15-20 years.

    ‘Modest effect’

    Patients in this trial, which was funded by drug company Novartis, had had MS for an average of 17 years – four years with secondary MS, the advanced stage.

    Most needed assistance with walking before the trial began.

    When standard measures of disability were used to track their progress, there was a 21% lower risk of walking or arm movements getting worse for those given the drug, compared with those taking the placebo.

    But the international research team found the drug had no effect on maintaining patients’ walking speed and it had some side-effects, although it was still thought to be safe.

    • How I’m feeling after my MS ‘body reboot’ – BBC News
      • Transplant trial gives us our future back

        Lead author Prof Ludwig Kappos, from the University of Basel, said: “Although the results are not as good as we wanted to see, it is a very large study, which is robust.

        “It means siponimod is one option to delay the disease in the advanced stage.”

        Dr Susan Kohlhaas, director of research at the MS Society, said: “These results bring us closer to the first ever treatment for people with secondary-progressive MS – so it’s big news.

        “This trial showed that siponimod had a modest but significant effect in slowing disability progression, which is incredibly encouraging.”

        ‘Disappointing’

        But Dr Luanne Metz, from the University of Calgary, in Canada, said a second trial was needed to confirm the benefits of the drug and its impact beyond three to six months.

        She said: “Although siponimod seems to reduce the time to confirmed disability in secondary-progressive MS, the treatment effect was small.

        “In our opinion… the absence of a significant difference for the key secondary clinical outcome are disappointing results and do not suggest that siponimod is an effective treatment for secondary-progressive MS.”

        She added: “Trials of other novel treatments that target non-inflammatory mechanisms are still needed.”

        Before the drug becomes available on the NHS, it would need to be approved by the European Medicines Agency and then recommended as cost-effective by bodies in the UK.